The bipolar disorder center had a great article about bipolar issues with natural "remedies" and I wanted to address it especially because I was contacted by a coach from another company that was feeling that agitated feeling after using their meal replacement shake. I have often shared my concern for those that don't realize that herbal remedies are great, but can work just as powerfully to harm someone as help them without the right information. The center shared all of these items that have been known to cause that feeling

Black cohosh (Cimicifuga racemosa). A nervous system depressant and sedative, sometimes used by people with autoimmune conditions for its anti-inflammatory effects. Its active ingredient appears to bind to estrogen receptor sites, so it may cause hormonal activity.

• Damiana (Turnera aphrodisiaca). A traditional remedy for depression. As its Latin name indicates, it is also believed to have aphrodisiac properties. Whatever the case may be there, it does seem to act on the hormonal system. Its energizing quality might be dangerous for bipolar patients. 
• Gingko biloba. An extract of the gingko tree, advertised as an herb that can improve your memory. There is some clinical evidence for this claim. It is an antioxidant, and is prescribed in Germany for treatment of dementia. It is believed to increase blood flow to the brain.
• Ginseng (Panax quinquefolium). Has an energizing effect that may be helpful to people whose depression is accompanied by extreme fatigue and lethargy.\
• Grapeseed oil and pycogenol. Both are extra-powerful antioxidants. (Pycogenol is derived from marine pine trees.)
• Gotu kola (Centella asiatica, Hydrocotyl asiatica). An Ayurvedic herbal stimulant sometimes recommended for depression and anxiety.
• Licorice (Glycyrrhiza glabra, Liquiritia officinalis). Boosts hormone production, including hormones active in the digestive tract and brain.
• Sarsaparilla (Hemidesmus indicus). Like licorice, it seems to affect hormone production as well as settling the stomach and calming the nerves.
• St. John's Wort (Hypericum perforatum). Has gained popularity as an herbal antidepressant. It has the backing of a decent amount of research. Those choosing to use this remedy should follow the same precautions as with SSRIs and MAOIs, two families of pharmaceutical antidepressants. It can also cause increased sensitivity to light. It is available by prescription in Germany, where it is the most widely used antidepressant. It is potentially dangerous to use St. John's Wort with prescription antidepressants or any other medication that could affect serotonin.